Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NDE1 All Species: 26.67
Human Site: S337 Identified Species: 48.89
UniProt: Q9NXR1 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NXR1 NP_001137451.1 346 38808 S337 M S S S P L P S A Q G V V K M
Chimpanzee Pan troglodytes XP_510841 506 54847 S497 M S S S P L P S A Q G V V K M
Rhesus Macaque Macaca mulatta XP_001109585 346 38722 S337 M S S S P L P S A Q G V V K M
Dog Lupus familis XP_545332 231 27040 S223 P I A H R G P S T S W V K M L
Cat Felis silvestris
Mouse Mus musculus Q9CZA6 344 38504 S335 P A S P A L P S A Q G V V K L
Rat Rattus norvegicus Q9ES39 344 38509 S335 L S S P A L P S T Q G V V K L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508695 347 38988 S338 G P P Q S L P S P Q G V V K M
Chicken Gallus gallus Q5ZMC9 342 39546 S334 P G P M S H P S Q S V V K M L
Frog Xenopus laevis Q66J96 349 39692 S340 T P M Q G M H S P Q G V V K M
Zebra Danio Brachydanio rerio Q803Q2 344 38425 S335 I A S P R A V S P P G L L P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VT70 317 36220 P310 Q F S V I H K P Q I R N P I T
Honey Bee Apis mellifera XP_393385 327 37894 I318 V H T S P H C I W Q Q P R S T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06568 189 21512 V182 T Q I T Q S T V I A T T S S V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 58.2 99.4 65.3 N.A. 89.3 85.5 N.A. 83.5 77.4 70.1 54.3 N.A. 30.9 33.5 N.A. N.A.
Protein Similarity: 100 62 99.7 65.9 N.A. 93.3 90.4 N.A. 89 83.8 79 70.5 N.A. 47.1 46.8 N.A. N.A.
P-Site Identity: 100 100 100 20 N.A. 66.6 66.6 N.A. 60 20 46.6 20 N.A. 6.6 20 N.A. N.A.
P-Site Similarity: 100 100 100 33.3 N.A. 80 80 N.A. 60 26.6 53.3 53.3 N.A. 6.6 33.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 36.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 8 0 16 8 0 0 31 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 8 0 0 8 8 0 0 0 0 62 0 0 0 0 % G
% His: 0 8 0 8 0 24 8 0 0 0 0 0 0 0 0 % H
% Ile: 8 8 8 0 8 0 0 8 8 8 0 0 0 8 0 % I
% Lys: 0 0 0 0 0 0 8 0 0 0 0 0 16 54 0 % K
% Leu: 8 0 0 0 0 47 0 0 0 0 0 8 8 0 39 % L
% Met: 24 0 8 8 0 8 0 0 0 0 0 0 0 16 39 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % N
% Pro: 24 16 16 24 31 0 62 8 24 8 0 8 8 8 0 % P
% Gln: 8 8 0 16 8 0 0 0 16 62 8 0 0 0 0 % Q
% Arg: 0 0 0 0 16 0 0 0 0 0 8 0 8 0 0 % R
% Ser: 0 31 54 31 16 8 0 77 0 16 0 0 8 16 0 % S
% Thr: 16 0 8 8 0 0 8 0 16 0 8 8 0 0 16 % T
% Val: 8 0 0 8 0 0 8 8 0 0 8 70 54 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _